.

Faculty Profile

Dr. Sneh Lata

Assistant Professor
Department of Chemistry
Atma Ram Sanatan Dharma College,
University of Delhi
Dhaula Kuan, New Delhi-110021
E-mail: sneh05@gmail.com

Educational Qualification

  • Ph.D. (2005-2010)-in Chemistry: "Designing, Synthesis and Biological Screening of Peptidomimics as Angiotensin Converting Enzyme Inhibitors". Department of Chemistry, University of Delhi & Institute of Genomics and Integrative Biology (IGIB), CSIR, Delhi.
  • M.Sc. (2002-2004)-Organic Chemistry, Miranda House, Department of Chemistry, University of Delhi.
  • B.Sc. (1999-2002)-Chemistry (H), Daulat Ram College, Department of Chemistry, University of Delhi.
  • National Eligibility Test (NET) - Conducted by Council of Scientific and Industrial Research (CSIR) and University Grant Commission on June 2005.

Career Profile

  • Teaching Experience: 8 years (Approx.)
  • Worked as Research Scientist in Jubilant Chemsys Pvt. Ltd.
  • Working as Assistant Professor in Department of Chemistry, Atma Ram Sanatan Dharma College, University of Delhi, Delhi.

Areas of Specialization / Interest

Medicinal Chemistry, Peptide Chemistry & Peptidomimmetics

Publications Profile

  1. Snehlata, Seth MK, Vats ID, Kumar K, Biswas P, Karar J, Hussain ME, Pasha M, Pasha S. Sulphur Containing Angiotensin Converting Enzyme Inhibitor- 3-Thienylalanine-Ornithyl-Proline Activates Endothelial Function and Expression of Genes Involved in Renin Angiotensin System. J Cardiovasc Pharmacol. 2012 Dec 7.
  2. Snehlata*, Hanif K*, Pavar MC, Arif E, Fahim M, Pasha MA, Pasha S. Effect of 3-thienylalanine-ornithine-proline, new sulfur-containing angiotensin-converting enzyme inhibitor on blood pressure and oxidative stress in spontaneously hypertensive rats. J Cardiovasc Pharmacol. (2009) 53(2):145-50. * authors have equal contribution
  3. Snehlata, Vats ID, Madhu Chopra, Parbati Biswas, Santosh Pasha. Effect of Varying Chain Length between P1 and P1' Position of Tripeptidomimics on Activity of Angiotensin Converting Enzyme Inhibitors. Bioorganic and Medicinal Letters (2009) 19: 4364-4366.
  4. Vats ID, Snehlata, Karar J, Nath M, Pasha MAQ, Pasha S. Endogenous Peptide: Met-Enkephalin-Arg-Phe, Differently Regulate Expression of Opioid Receptors on Chronic Treatment. Neuropeptides (2009) 43 (5):355-62.
  5. Vats ID, Snehlata, Nath M, Pasha S. Effect of Chronic Intra-Peritoneally Administered Chimeric Peptide of Met-Enkephalin and FMRFa-[D-Ala2]YFa-on Antinociception and Opioid Receptor Regulation. Europeon Journal of Pain. (2010) 14 (3):295e1-9.
  6. Vats ID, Snehlata, Ahuti Sharma, Nath M, Pasha S. Modified Chimeric Peptide of Met-Enkephalin and FMRFa-[D-Ala2, p-Cl-Phe4]YFa-Induce Non-Specific Antinociception and Up-regulate Opioid Receptor Expression. European Journal of Pharmacology (2010) 638 (1-3):54-60.
  7. Pavar MC, Hanif K, Azam A, Snehlata, Qadar Pasha MA, Pasha S. Structure-activity relationship study between Ornithyl-Proline and Lysyl-Proline based tripeptidomimics as angiotensin-converting enzyme inhibitors. Bioorg Med Chem Lett. (2006) 16(8):2117-21.
  8.  Vats ID, Snehlata, Mahendra Nath, Santosh Pasha. Role of C Terminal -RFamide- site of chimeric opioid peptide of Met-enkephalin and FMRFa in antinociception and opioid receptor specificity. (Under revision in Neuropeptides)
Conference Participation / Presentations

PRESENTATIONS:

International Presentations:

  1. Effect of 3-Thienylalanine-Ornithine-Proline on L-NAME Induced Hypertension in Rats. Mahesh Kumar Seth, Snehlata, M.Fahim, M.Ejaz Hussain, Santosh Pasha. 14th ISCBC-2010 International Conference on Interplay of Chemical and Biological Sciences: Impact on Health and Environment
  2. Structure Activity Relationship of Different Hydrophobic Residues at P1' Position of Tripeptidomimics as Angiotensin-Converting Enzyme Inhibitors. Snehlata, Mahesh C Pavar, P Biswas, Santosh Pasha. 13th ISCBC-2009 International Conference on Interplay of Chemical and Biological Sciences: Impact on Health and Environment
  3. Effect of Hydrophobic Residues at the P1' Position of Tripeptidomimics on their Angiotensin Converting Enzyme Inhibition Potency. Snehlata, Mahesh Chand Pavar­, K. Hanif, P. Biswas, Santosh Pasha. Zing International Medicinal Chemistry Conference, 2009.
  4. In-Vivo Studies of New Sulphur Containing ACE Inhibitor-3-Thienylalanine-Ornithine-Proline and its Comparison with Captopril on Blood Pressure. Snehlata, Kashif Hanif, M.C. Pavar, P. Biswas, MAQ Pasha, Santosh Pasha. 1st International Conference on Drug Design & Discovery, 2008.

National Presentation:

  • Thienylalanine-Ornithine-Proline: new sulphur containing ACE inhibitor   and   its comparison with captopril on ACE inhibition and NO level in SHRs. Snehlata, Kashif Hanif, M.C. Pavar, P. Biswas, MAQ Pasha, Santosh Pasha. 1st Indian Peptide Symposium, 2007. 

CONFERENCE/SYMPOSIUM ATTENDED:

  • Technical Terminology in Science Teaching conducted by MHRD, Deshbandhu College, University of Delhi from October 26-27, 2017
  • Participated in Workshop on Molecular Modeling, ARSD, University of Delhi,on 23rd Jan, 2018
  • 9th CRSI National Symposium in Chemistry (NSC-9) 2006.
  • 2nd Indian Peptide Symposium 2009.

 

Other Activities

MEMBERSHIP:

  • Indian Peptide Society.
  • Member of Indian Science Congress Association.

AWARDS:

  • Awarded 100% travel grant for attending conference in Mexico, from Department of Science and Technology, Govt. of India and Council of Scientific and Industrial Research, Govt. of India.